RAF Typhoon jets have joined forces with French aircraft in a coordinated attack targeting an subterranean weapons facility in Syria operated by the IS group, per a report from the UK's MoD.
The site, located using intelligence, was believed to be storing arms and explosives, the statement said, and was situated in mountainous terrain just above the ancient city of Palmyra in central Syria.
"Our fighter planes employed Paveway IV guided bombs to hit a series of approach shafts leading to the facility... early reports are that the strike was effective," the ministry announced.
There was no sign of any harm to civilians in the strike on Saturday evening and all the aircraft returned to base without incident, the ministry further stated.
The Typhoon fighters were supported by a Voyager refuelling tanker.
IS - alternatively referred to as ISIS - established militant control over significant areas in Syria and Iraq until 2019.
"This strike demonstrates our UK leadership, and commitment to operate in unison with allied nations, to eliminate any revival of Daesh and their violent and radical beliefs in the area," UK Defence Secretary the minister said.
British military aircraft have performed patrols over Syrian airspace to "prevent any efforts to regroup" of IS after its routing at the battle of Baghuz in 2019, the MoD reported.
"I extend gratitude to all the members of the UK armed forces involved in this operation for their skill and their courage," the Defence Secretary added. "Including them were numerous British personnel on duty over the festive period. This mission, to take out terrorist threats who threaten our security, demonstrates how UK forces are prepared to act, throughout the year, keeping Britain secure domestically and strong abroad."
During December, the US military conducted what it termed a "massive strike" against Daesh sites in the country, following an attack claimed the lives of two US servicemembers and a civilian linguist in the Palmyra area.
The U.N. reports Daesh still maintains roughly 5-7 thousand militants in both countries.